Reolin is characterized by a precise release profile. The high bioavailability combined with a sufficiently long-time iron release offers an optimal absorption by the body, consequently reducing unused ions’ harmful excess.
In Vitro study was carried out under the conditions simulating the small intestine by using the following strains:
- coli ATCC 95922
- Enterococcus faecalis ATCC2912
- Staphylococcus aureus with the MRSA ATCC-BAA-36 mechanism
The same culture suspension density of 102/103 cfu/ml was used for all pathogenic microorganisms. The selected strains represent the flora of the human digestive tract and are of paramount importance because these strains are the main cause of sepsis (11, 12, 13, 14, 15, 17, 18, and 20)
8.5 μM of iron Reol was used as a source, and the preparation with particles’ size of 5.2 μM (median D50) was employed as reference. The same amount of 300 μl of both iron sources was used. A sample of 300 μl bacterial suspension was putin an Ependroff test tube, and 300 μl of the corresponding Reol or reference sample was added. Following incubation at 37°C±1°C, the measurements were carried out after 30 min, 8h, 24h, merely using the aqueous phase.